The most problematic situation arises when symptoms occur in the middle trimester. At that time, it is suggested that bromocriptine therapy is restarted in the hope of reducing the tumour size or at least preventing further swelling. If this is unsuccessful, high-dose dexamethasone can be used to achieve the same ends.
Dexamethasone also reduces the chances of foetal respiratory distress occurring should premature delivery be needed. As a last resort, transsphenoidal surgery during pregnancy can, and has been, used to decompress the tumour. Since such complications are extremely rare, however, little data have to date been accumulated.
